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README.md

Quick reference

HH-suite | openEuler

HH-suite3 is an open-source software package for sensitive protein sequence searching based on the pairwise alignment of hidden Markov models (HMMs), developed by the Soding lab. HH-suite provides:

  • HHblits: Fast iterative HMM search for remote homology detection and deep protein annotation.
  • HHsearch: Sensitive HMM-HMM alignment for profile-profile comparison.
  • HHPred: Protein structure and function prediction via profile-profile search.
  • SIMD acceleration: SSE2/AVX2 on x86_64, NEON on ARM64 for high-performance sequence alignment.
  • MPI parallel computation support (self-compiled version only).
  • Multi-format input support: FASTA, A3M, HMM, and HHM profiles.
  • Extensive database integration: Uniclust30, BFD, Pfam, SCOP, PDB70, and more. Learn more at HH-suite.

Supported tags and respective Dockerfile links

The tag of each HH-suite docker image is consist of the version of HH-suite and the version of basic image. The details are as follows:

Tags Currently Architectures
3.3.0-oe2403sp3 HH-suite 3.3.0 on openEuler 24.03-LTS-SP3 amd64, arm64

Usage

  • Ensure that you have Docker installed, or are using Docker for Linux containers if on Windows.
  • Obtain the HH-suite docker image from DockerHub: docker pull openeuler/hh-suite:{Tag}
  • Run the Docker container to launch the HH-suite environment. docker run -it openeuler/hh-suite:{Tag}
  • Verify the installation inside the container: hhblits -h && hhsearch -h

Question and answering

If you have any questions or want to use some special features, please submit an issue or a pull request on openeuler-docker-images.