import numpy as np
from ..fixes import rng_uniform
from ..label import Label
from ..source_estimate import SourceEstimate, VolSourceEstimate
from ..source_space._source_space import _ensure_src
from ..surface import _compute_nearest
from ..utils import (
_check_option,
_ensure_events,
_ensure_int,
_legacy_rng,
_validate_type,
fill_doc_static,
warn,
)
@_legacy_rng("random_state")
@fill_doc_static("subjects_dir", "rng", "random_state_rng")
def select_source_in_label(
src,
label,
location="random",
subject=None,
subjects_dir=None,
surf="sphere",
*,
rng=None,
random_state=None,
):
"""Select source positions using a label.
Parameters
----------
src : list of dict
The source space.
label : Label
The label.
location : str
The label location to choose. Can be 'random' (default) or 'center'
to use :func:`mne.Label.center_of_mass` (restricting to vertices
both in the label and in the source space). Note that for 'center'
mode the label values are used as weights.
.. versionadded:: 0.13
subject : str | None
The subject the label is defined for.
Only used with ``location='center'``.
.. versionadded:: 0.13
subjects_dir : path-like | None
The path to the directory containing the FreeSurfer subjects
reconstructions. If ``None``, defaults to the ``SUBJECTS_DIR`` environment
variable.
.. versionadded:: 0.13
surf : str
The surface to use for Euclidean distance center of mass
finding. The default here is "sphere", which finds the center
of mass on the spherical surface to help avoid potential issues
with cortical folding.
.. versionadded:: 0.13
rng : None | int | instance of ~numpy.random.Generator | ~numpy.random.RandomState
The random number generator (RNG). If ``None`` (default), a new
:class:`numpy.random.Generator` seeded from entropy is used. Pass an int or
a :class:`numpy.random.Generator` for reproducible results, or a legacy
:class:`~numpy.random.RandomState` to control the random-number stream or
for interoperability with third-party code such as scikit-learn that does
not accept generators. An integer seed uses
:func:`numpy.random.default_rng` and therefore produces a different stream
than the same integer passed to a legacy ``random_state`` or ``seed``
parameter.
.. versionadded:: 1.13
random_state : None | int | instance of ~numpy.random.RandomState
Supported for compatibility. New code should use ``rng``. If ``None``,
NumPy's global :class:`~numpy.random.RandomState` is used.
Returns
-------
lh_vertno : list
Selected source coefficients on the left hemisphere.
rh_vertno : list
Selected source coefficients on the right hemisphere.
"""
return _select_source_in_label(
src,
label,
location=location,
subject=subject,
subjects_dir=subjects_dir,
surf=surf,
rng=rng,
)
def _select_source_in_label(src, label, *, location, subject, subjects_dir, surf, rng):
"""Select a source in a label using an already normalized RNG."""
lh_vertno = list()
rh_vertno = list()
_check_option("location", location, ["random", "center"])
if label.hemi == "lh":
vertno = lh_vertno
hemi_idx = 0
else:
vertno = rh_vertno
hemi_idx = 1
src_sel = np.intersect1d(src[hemi_idx]["vertno"], label.vertices)
if location == "random":
idx = src_sel[rng_uniform(rng)(0, len(src_sel), 1)[0]]
else:
idx = label.center_of_mass(
subject, restrict_vertices=src_sel, subjects_dir=subjects_dir, surf=surf
)
vertno.append(idx)
return lh_vertno, rh_vertno
@_legacy_rng("random_state")
@fill_doc_static("subjects_dir", "rng", "random_state_rng")
def simulate_sparse_stc(
src,
n_dipoles,
times,
data_fun=lambda t: 1e-7 * np.sin(20 * np.pi * t),
labels=None,
location="random",
subject=None,
subjects_dir=None,
surf="sphere",
*,
rng=None,
random_state=None,
):
"""Generate sparse (n_dipoles) sources time courses from data_fun.
This function randomly selects ``n_dipoles`` vertices in the whole
cortex or one single vertex (randomly in or in the center of) each
label if ``labels is not None``. It uses ``data_fun`` to generate
waveforms for each vertex.
Parameters
----------
src : instance of SourceSpaces
The source space.
n_dipoles : int
Number of dipoles to simulate.
times : array
Time array.
data_fun : callable
Function to generate the waveforms. The default is a 100 nAm, 10 Hz
sinusoid as ``1e-7 * np.sin(20 * pi * t)``. The function should take
as input the array of time samples in seconds and return an array of
the same length containing the time courses.
labels : None | list of Label
The labels. The default is None, otherwise its size must be n_dipoles.
location : str
The label location to choose. Can be ``'random'`` (default) or
``'center'`` to use :func:`mne.Label.center_of_mass`. Note that for
``'center'`` mode the label values are used as weights.
.. versionadded:: 0.13
subject : str | None
The subject the label is defined for.
Only used with ``location='center'``.
.. versionadded:: 0.13
subjects_dir : path-like | None
The path to the directory containing the FreeSurfer subjects
reconstructions. If ``None``, defaults to the ``SUBJECTS_DIR`` environment
variable.
.. versionadded:: 0.13
surf : str
The surface to use for Euclidean distance center of mass
finding. The default here is "sphere", which finds the center
of mass on the spherical surface to help avoid potential issues
with cortical folding.
.. versionadded:: 0.13
rng : None | int | instance of ~numpy.random.Generator | ~numpy.random.RandomState
The random number generator (RNG). If ``None`` (default), a new
:class:`numpy.random.Generator` seeded from entropy is used. Pass an int or
a :class:`numpy.random.Generator` for reproducible results, or a legacy
:class:`~numpy.random.RandomState` to control the random-number stream or
for interoperability with third-party code such as scikit-learn that does
not accept generators. An integer seed uses
:func:`numpy.random.default_rng` and therefore produces a different stream
than the same integer passed to a legacy ``random_state`` or ``seed``
parameter.
.. versionadded:: 1.13
random_state : None | int | instance of ~numpy.random.RandomState
Supported for compatibility. New code should use ``rng``. If ``None``,
NumPy's global :class:`~numpy.random.RandomState` is used.
Returns
-------
stc : SourceEstimate
The generated source time courses.
See Also
--------
simulate_raw
simulate_evoked
simulate_stc
Notes
-----
.. versionadded:: 0.10.0
"""
src = _ensure_src(src, verbose=False)
subject_src = src._subject
if subject is None:
subject = subject_src
elif subject_src is not None and subject != subject_src:
raise ValueError(
f"subject argument ({subject}) did not match the source "
f"space subject_his_id ({subject_src})"
)
data = np.zeros((n_dipoles, len(times)))
for i_dip in range(n_dipoles):
data[i_dip, :] = data_fun(times)
if labels is None:
offsets = np.linspace(0, n_dipoles, len(src) + 1).astype(int)
n_dipoles_ss = np.diff(offsets)
vs = [
s["vertno"][np.sort(rng.permutation(np.arange(s["nuse"]))[:n])]
for n, s in zip(n_dipoles_ss, src)
]
datas = data
elif n_dipoles > len(labels):
raise ValueError(
f"Number of labels ({len(labels)}) smaller than n_dipoles ({n_dipoles:d}) "
"is not allowed."
)
else:
if n_dipoles != len(labels):
warn(
"The number of labels is different from the number of "
f"dipoles. {min(n_dipoles, len(labels))} dipole(s) will be generated."
)
labels = labels[:n_dipoles] if n_dipoles < len(labels) else labels
vertno = [[], []]
lh_data = [np.empty((0, data.shape[1]))]
rh_data = [np.empty((0, data.shape[1]))]
for i, label in enumerate(labels):
lh_vertno, rh_vertno = _select_source_in_label(
src,
label,
location=location,
subject=subject,
subjects_dir=subjects_dir,
surf=surf,
rng=rng,
)
vertno[0] += lh_vertno
vertno[1] += rh_vertno
if len(lh_vertno) != 0:
lh_data.append(data[i][np.newaxis])
elif len(rh_vertno) != 0:
rh_data.append(data[i][np.newaxis])
else:
raise ValueError("No vertno found.")
vs = [np.array(v) for v in vertno]
datas = [np.concatenate(d) for d in [lh_data, rh_data]]
for ii in range(2):
order = np.argsort(vs[ii])
vs[ii] = vs[ii][order]
if len(order) > 0:
datas[ii] = datas[ii][order]
datas = np.concatenate(datas)
tmin, tstep = times[0], np.diff(times[:2])[0]
assert datas.shape == data.shape
cls = SourceEstimate if len(vs) == 2 else VolSourceEstimate
stc = cls(datas, vertices=vs, tmin=tmin, tstep=tstep, subject=subject)
return stc
def simulate_stc(
src, labels, stc_data, tmin, tstep, value_fun=None, allow_overlap=False
):
"""Simulate sources time courses from waveforms and labels.
This function generates a source estimate with extended sources by
filling the labels with the waveforms given in stc_data.
Parameters
----------
src : instance of SourceSpaces
The source space.
labels : list of Label
The labels.
stc_data : array, shape (n_labels, n_times)
The waveforms.
tmin : float
The beginning of the timeseries.
tstep : float
The time step (1 / sampling frequency).
value_fun : callable | None
Function to apply to the label values to obtain the waveform
scaling for each vertex in the label. If None (default), uniform
scaling is used.
allow_overlap : bool
Allow overlapping labels or not. Default value is False.
.. versionadded:: 0.18
Returns
-------
stc : SourceEstimate
The generated source time courses.
See Also
--------
simulate_raw
simulate_evoked
simulate_sparse_stc
"""
if len(labels) != len(stc_data):
raise ValueError("labels and stc_data must have the same length")
vertno = [[], []]
stc_data_extended = [[], []]
hemi_to_ind = {"lh": 0, "rh": 1}
for i, label in enumerate(labels):
hemi_ind = hemi_to_ind[label.hemi]
src_sel = np.intersect1d(src[hemi_ind]["vertno"], label.vertices)
if len(src_sel) == 0:
idx = src[hemi_ind]["inuse"].astype("bool")
xhs = src[hemi_ind]["rr"][idx]
rr = src[hemi_ind]["rr"][label.vertices]
closest_src = _compute_nearest(xhs, rr)
src_sel = src[hemi_ind]["vertno"][np.unique(closest_src)]
if value_fun is not None:
idx_sel = np.searchsorted(label.vertices, src_sel)
values_sel = np.array([value_fun(v) for v in label.values[idx_sel]])
data = np.outer(values_sel, stc_data[i])
else:
data = np.tile(stc_data[i], (len(src_sel), 1))
if allow_overlap:
duplicates = []
for src_ind, vertex_ind in enumerate(src_sel):
ind = np.where(vertex_ind == vertno[hemi_ind])[0]
if len(ind) > 0:
assert len(ind) == 1
stc_data_extended[hemi_ind][ind[0]] += data[src_ind]
duplicates.append(src_ind)
data = np.delete(data, duplicates, axis=0)
src_sel = list(np.delete(np.array(src_sel), duplicates))
vertno[hemi_ind].extend(src_sel)
stc_data_extended[hemi_ind].extend(np.atleast_2d(data))
vertno = [np.array(v) for v in vertno]
if not allow_overlap:
for v, hemi in zip(vertno, ("left", "right")):
d = len(v) - len(np.unique(v))
if d > 0:
raise RuntimeError(
f"Labels had {d} overlaps in the {hemi} "
"hemisphere, they must be non-overlapping"
)
data = list()
for i in range(2):
if len(stc_data_extended[i]) != 0:
stc_data_extended[i] = np.vstack(stc_data_extended[i])
idx = np.argsort(vertno[i])
data.append(stc_data_extended[i][idx])
vertno[i] = vertno[i][idx]
stc = SourceEstimate(
np.concatenate(data),
vertices=vertno,
tmin=tmin,
tstep=tstep,
subject=src._subject,
)
return stc
class SourceSimulator:
"""Class to generate simulated Source Estimates.
Parameters
----------
src : instance of SourceSpaces
Source space.
tstep : float
Time step between successive samples in data. Default is 0.001 s.
duration : float | None
Time interval during which the simulation takes place in seconds.
If None, it is computed using existing events and waveform lengths.
first_samp : int
First sample from which the simulation takes place, as an integer.
Comparable to the :term:`first_samp` property of `~mne.io.Raw` objects.
Default is 0.
Attributes
----------
duration : float
The duration of the simulation in seconds.
n_times : int
The number of time samples of the simulation.
"""
def __init__(self, src, tstep=1e-3, duration=None, first_samp=0):
if duration is not None and duration < tstep:
raise ValueError("duration must be None or >= tstep.")
self.first_samp = _ensure_int(first_samp, "first_samp")
self._src = src
self._tstep = tstep
self._labels = []
self._waveforms = []
self._events = np.empty((0, 3), dtype=int)
self._duration = duration
self._last_samples = []
self._chk_duration = 1000
@property
def duration(self):
"""Duration of the simulation in same units as tstep."""
if self._duration is not None:
return self._duration
return self.n_times * self._tstep
@property
def n_times(self):
"""Number of time samples in the simulation."""
if self._duration is not None:
return int(self._duration / self._tstep)
ls = self.first_samp
if len(self._last_samples) > 0:
ls = np.max(self._last_samples)
return ls - self.first_samp + 1
@property
def last_samp(self):
return self.first_samp + self.n_times - 1
def add_data(self, label, waveform, events):
"""Add data to the simulation.
Data should be added in the form of a triplet of
Label (Where) - Waveform(s) (What) - Event(s) (When)
Parameters
----------
label : instance of Label
The label (as created for example by mne.read_label). If the label
does not match any sources in the SourceEstimate, a ValueError is
raised.
waveform : array, shape (n_times,) or (n_events, n_times) | list
The waveform(s) describing the activity on the label vertices.
If list, it must have the same length as events.
events : array of int, shape (n_events, 3)
Events associated to the waveform(s) to specify when the activity
should occur.
"""
_validate_type(label, Label, "label")
if not isinstance(waveform, list) and np.ndim(waveform) == 2:
waveform = list(waveform)
if not isinstance(waveform, list) and np.ndim(waveform) == 1:
waveform = [waveform]
if len(waveform) == 1:
waveform = waveform * len(events)
if len(waveform) != len(events):
raise ValueError(
"Number of waveforms and events should match or "
f"there should be a single waveform ({len(waveform)} != {len(events)})."
)
events = _ensure_events(events).astype(np.int64)
self._labels.extend([label] * len(events))
self._waveforms.extend(waveform)
self._events = np.concatenate([self._events, events])
assert self._events.dtype == np.int64
self._last_samples = np.array(
[self._events[i, 0] + len(w) - 1 for i, w in enumerate(self._waveforms)]
)
def get_stim_channel(self, start_sample=0, stop_sample=None):
"""Get the stim channel from the provided data.
Returns the stim channel data according to the simulation parameters
which should be added through the add_data method. If both start_sample
and stop_sample are not specified, the entire duration is used.
Parameters
----------
start_sample : int
First sample in chunk. Default is the value of the ``first_samp``
attribute.
stop_sample : int | None
The final sample of the returned stc. If None, then all samples
from start_sample onward are returned.
Returns
-------
stim_data : ndarray of int, shape (n_samples,)
The stimulation channel data.
"""
if start_sample is None:
start_sample = self.first_samp
if stop_sample is None:
stop_sample = start_sample + self.n_times - 1
elif stop_sample < start_sample:
raise ValueError("Argument start_sample must be >= stop_sample.")
n_samples = stop_sample - start_sample + 1
stim_data = np.zeros(n_samples, dtype=np.int64)
stim_ind = np.where(
np.logical_and(
self._events[:, 0] >= start_sample, self._events[:, 0] < stop_sample
)
)[0]
if len(stim_ind) > 0:
relative_ind = self._events[stim_ind, 0] - start_sample
stim_data[relative_ind] = self._events[stim_ind, 2]
return stim_data
def get_stc(self, start_sample=None, stop_sample=None):
"""Simulate a SourceEstimate from the provided data.
Returns a SourceEstimate object constructed according to the simulation
parameters which should be added through function add_data. If both
start_sample and stop_sample are not specified, the entire duration is
used.
Parameters
----------
start_sample : int | None
First sample in chunk. If ``None`` the value of the ``first_samp``
attribute is used. Defaults to ``None``.
stop_sample : int | None
The final sample of the returned STC. If ``None``, then all samples
past ``start_sample`` are returned.
Returns
-------
stc : SourceEstimate object
The generated source time courses.
"""
if len(self._labels) == 0:
raise ValueError(
"No simulation parameters were found. Please use "
"function add_data to add simulation parameters."
)
if start_sample is None:
start_sample = self.first_samp
if stop_sample is None:
stop_sample = start_sample + self.n_times - 1
elif stop_sample < start_sample:
raise ValueError("start_sample must be >= stop_sample.")
n_samples = stop_sample - start_sample + 1
stc_data = np.zeros((len(self._labels), n_samples))
ind = np.where(
np.logical_and(
self._last_samples >= start_sample, self._events[:, 0] <= stop_sample
)
)[0]
subset_waveforms = [self._waveforms[i] for i in ind]
for i, (waveform, event) in enumerate(zip(subset_waveforms, self._events[ind])):
wf_start = event[0]
wf_stop = self._last_samples[ind[i]]
waveform_ind = np.isin(
np.arange(wf_start, wf_stop + 1),
np.arange(start_sample, stop_sample + 1),
)
stc_ind = np.isin(
np.arange(start_sample, stop_sample + 1),
np.arange(wf_start, wf_stop + 1),
)
stc_data[ind[i]][stc_ind] += waveform[waveform_ind]
start_sample -= self.first_samp
stc = simulate_stc(
self._src,
self._labels,
stc_data,
start_sample * self._tstep,
self._tstep,
allow_overlap=True,
)
return stc
def __iter__(self):
"""Iterate over 1 second STCs.
Yields
------
stc : instance of SourceEstimate
The source estimate for the next chunk of data.
stim : ndarray, shape (n_samples,)
The stim channel for the same chunk.
"""
last_sample = self.last_samp
for start_sample in range(self.first_samp, last_sample + 1, self._chk_duration):
stop_sample = min(start_sample + self._chk_duration - 1, last_sample)
yield (
self.get_stc(start_sample, stop_sample),
self.get_stim_channel(start_sample, stop_sample),
)